You can associate Help topics with controls using the Select Help Topic dialog box.
Unchecking Use default events allows you to specify the events on a per-control basis. Otherwise, the DefaultTrigger property is used for all controls. Using the Events settings makes showing topics automatic when a control obtains focus or the mouse hovers over it, or in both cases. But if you want manual control over what triggers topic display, you can uncheck both check boxes (or set DefaultTrigger=None; this will do it for all controls if it's not overridden on a per-control basis) and show topics programmatically.